What do systematic reviews say?

DOAC vs heparin

DOAC showed no clear difference in symptomatic VTE (DVT and PE) Treatment duration 28 ‐ 42 days compared with heparin (low certainty).

• Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or… 2016 · Cochrane Headline outcomes only
  OR 0.7 [0.28, 1.7]
  5 studies · 15977 participants
  Low