Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Common Mental Disorders

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No studies found 3 · 60%GRADE not reported 0 · 0%Very low 2 · 40%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Cytidine vs placebo

Efficacy: number of participants who respond to treatment ‐ at 3 months · adults (aged 18 years+) with depression in bipolar disorder

It is very uncertain whether cytidine changes efficacy: number of participants who respond to treatment ‐ at 3… compared with placebo (very low certainty).

1 finding from 1 review

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder 2021 · Cochrane Headline outcomes only
OR 1.13 [0.3, 4.24]
1 study · 35 participants
Very low

Cytidine vs placebo

Remission · adults (aged 18 years+) with depression in bipolar disorder

The review found no eligible studies for this question.

1 finding from 1 review

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cytidine vs placebo

Depression rating scale score · adults (aged 18 years+) with depression in bipolar disorder

The review found no eligible studies for this question.

1 finding from 1 review

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cytidine vs placebo

Acceptability ‐ total dropouts · adults (aged 18 years+) with depression in bipolar disorder

It is very uncertain whether cytidine changes acceptability: total dropouts compared with placebo (very low certainty).

1 finding from 1 review

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder 2021 · Cochrane Headline outcomes only
OR 0.94 [0.12, 7.52]
1 study · 35 participants
Very low

Cytidine vs placebo

Acceptability ‐ dropouts due to adverse effects · adults (aged 18 years+) with depression in bipolar disorder

The review found no eligible studies for this question.

1 finding from 1 review

Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found