Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Cranberry extract or cranberry flavonoid fractions vs No extract or vehicle control; other antimicrobial agents

Biofilm formation · Streptococcus mutans (in vitro cultures and biofilms)

No meta-analysis was conducted; ten included studies reported reduced or inhibited Streptococcus mutans biofilm formation with cranberry extract or fractions.

1 finding from 1 review

Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a… 2024 All outcomes
In vitro laboratory studies
no estimate extracted
10 studies
GRADE not reported

Cranberry extract / juice and proanthocyanidin (flavonoid) fractions vs Untreated or vehicle control (some studies vs positive antimicrobial controls, e.g. chlorhexidine/fluoride)

Biofilm formation (reduction) · Streptococcus mutans (in vitro cultures and biofilms)

Cranberry extract reduces S. mutans biofilm formation in vitro (10 studies; ungraded).

1 finding from 1 review

Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a… 2024 All outcomes
in vitro (laboratory)
Cranberry extract/PAC reduced S. mutans biofilm formation: 51% at 500 ug/mL (Philip 2019), 95.2% at 50 mg/mL (Sumathi), 50-70% of preformed biofilm at 16.67-20.83 mg/dL (Singhal), 32%/29%/14% at 500/250/125 ug/mL…
10 studies
GRADE not reported