Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Cranberry extract or cranberry flavonoid fractions vs No extract or vehicle control; other antimicrobial agents

Bacterial growth inhibition · Streptococcus mutans (in vitro cultures and biofilms)

No meta-analysis was conducted; seven included studies reported inhibition of Streptococcus mutans growth with cranberry extract or fractions.

1 finding from 1 review

Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a… 2024 All outcomes
In vitro laboratory studies
no estimate extracted
7 studies
GRADE not reported

Cranberry extract / juice and proanthocyanidin (flavonoid) fractions vs Untreated or vehicle control (some studies vs positive antimicrobial controls, e.g. chlorhexidine/fluoride)

Bacterial growth inhibition · Streptococcus mutans (in vitro cultures and biofilms)

Cranberry extract inhibits S. mutans growth in vitro (MIC ~0.5-60 mg/mL across 7 studies; ungraded).

1 finding from 1 review

Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a… 2024 All outcomes
in vitro (laboratory)
Cranberry extract inhibited S. mutans growth across ~0.5-25 mg/mL (Abstract): MIC 12.5 mg/dL and MBC 25 mg/dL (Singhal), MIC 60 mg/mL (Sumathi), MIC 0.5-0.75 mg/mL (Prince); 2 mg/mL PAC enhanced photo-irradiated H2O2…
7 studies
GRADE not reported