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What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 1 reviews · Gut

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No studies found 1 · 7.1%GRADE not reported 0 · 0%Very low 3 · 21.4%Low 7 · 50%Moderate 2 · 14.3%High 1 · 7.1%

Corticosteroids vs placebo

Histological improvement (dichotomous) · inactive EoE patients

Corticosteroids probably leads to higher histological improvement (dichotomous) compared with placebo (moderate certainty).

1 finding from 1 review

Corticosteroids vs placebo

Withdrawals due to adverse events · inactive EoE patients

Corticosteroids may leads to lower withdrawals due to adverse events 12 to 50 weeks compared with placebo (low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Histological improvement (dichotomous) · active EoE patients

Corticosteroids leads to higher histological improvement (dichotomous) compared with placebo (high certainty).

1 finding from 1 review

Corticosteroids vs placebo

Endoscopic improvement (dichotomous) · active EoE patients

Corticosteroids showed no clear difference in endoscopic improvement (dichotomous) compared with placebo (low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Withdrawals due to adverse events · active EoE patients

Corticosteroids may leads to lower withdrawals due to adverse events (2 to 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Clinical improvement (dichotomous) · inactive EoE patients

It is very uncertain whether corticosteroids changes clinical improvement (dichotomous) compared with placebo (very low certainty).

1 finding from 1 review