Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Neuromuscular

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 1 · 14.3%High 5 · 71.4%

Corticosteroids vs placebo compared

Death ‐ at 180 days after ICU admission, in total population randomised · critically ill patients

Corticosteroids showed no clear difference in death ‐ death at 180 days in total population randomised compared with placebo compared (high certainty).

1 finding from 1 review

Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
RR 0.99 [0.64, 1.52]
1 study · 180 participants
High

Corticosteroids vs placebo compared

Serious adverse events (dichotomous data) ‐ shock · critically ill patients

Corticosteroids showed no clear difference in serious adverse events (dichotomous data) ‐ shock compared with placebo compared (high certainty).

1 finding from 1 review

Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
RR 0.41 [0.17, 1.01]
1 study · 180 participants
High

Corticosteroids vs placebo compared

Serious adverse events (dichotomous data) ‐ serious infection · critically ill patients

Corticosteroids showed no clear difference in serious adverse events (dichotomous data) ‐ serious infection compared with placebo compared (high certainty).

1 finding from 1 review

Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
RR 0.68 [0.42, 1.11]
1 study · 180 participants
High

Corticosteroids vs placebo compared

Serious adverse events (dichotomous data) ‐ suspected or probable pneumonia · critically ill patients

Corticosteroids showed no clear difference in serious adverse events (dichotomous data) ‐ suspected or probable… compared with placebo compared (high certainty).

1 finding from 1 review

Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
RR 0.44 [0.18, 1.09]
1 study · 180 participants
High

Corticosteroids vs placebo compared

Serious adverse events (continuous data) ‐ blood glucose (mg/dL) on day 7 · critically ill patients

1 finding from 1 review

Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 180 participants
High

Corticosteroids vs placebo compared

Occurrence of CIP/CIM ‐ in the total population randomised · critically ill patients

Corticosteroids showed no clear difference in occurrence of CIP/CIM ‐ in total population randomised compared with placebo compared (low certainty).

1 finding from 1 review

Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
RR 1.27 [0.77, 2.08]
1 study · 180 participants
Low

Corticosteroids vs placebo compared

Occurrence of CIP/CIM ‐ in screened population · critically ill patients

Corticosteroids showed no clear difference in occurrence of CIP/CIM ‐ in screened population compared with placebo compared (moderate certainty).

1 finding from 1 review

Interventions for preventing critical illness polyneuropathy and critical illness myopathy 2014 · Cochrane Headline outcomes only
RR 1.09 [0.53, 2.26]
1 study · 92 participants
Moderate