Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

415 questions · 442 findings · 58 reviews

No studies found 70 · 15.8%GRADE not reported 19 · 4.3%Very low 99 · 22.4%Low 137 · 31%Moderate 86 · 19.5%High 31 · 7%

Intramuscular corticosteroids vs oral corticosteroid

Relapse · patients with acute asthma

Intramuscular corticosteroids showed no clear difference in relapse compared with oral corticosteroids (low certainty).

3 findings from 1 review

Systemic or topical corticosteroids vs placebo or control

Short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after treatment; oral corticosteroids · people with traumatic hyphema

Systemic or topical corticosteroids showed no clear difference in short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after… compared with placebo or control treatment (low certainty).

1 finding from 1 review

Systemic or topical corticosteroids vs placebo or control

Final visual acuity between 20/20 and 20/40 at end of treatment; oral corticosteroids · people with traumatic hyphema

Systemic or topical corticosteroids showed no clear difference in final visual acuity between 20/20 and 20/40 at end of treatment;… compared with placebo or control treatment (low certainty).

1 finding from 1 review

Systemic or topical corticosteroids vs placebo or control

Short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after treatment; topical corticosteroids · people with traumatic hyphema

It is very uncertain whether systemic or topical corticosteroids changes short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after… compared with placebo or control treatment (very low certainty).

1 finding from 1 review

Systemic or topical corticosteroids vs placebo or control

Final visual acuity between 20/20 and 20/25 at end of treatment; topical corticosteroids · people with traumatic hyphema

Systemic or topical corticosteroids showed no clear difference in final visual acuity between 20/20 and 20/25 at end of treatment;… compared with placebo or control treatment (low certainty).

1 finding from 1 review

Oral corticosteroids vs placebo or NSAID

Proportion of patients with resolution or improved symptoms at days 3 to 7 · patients with acute sinusitis

Oral corticosteroids probably leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (moderate certainty).

3 findings from 1 review

Oral corticosteroids vs placebo or NSAID

Proportion of patients with resolution or improved symptoms at days 4 to 14 · patients with acute sinusitis

Oral corticosteroids probably leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (moderate certainty).

2 findings from 1 review

Oral corticosteroids vs placebo or NSAID

Proportion of patients with resolution or improved symptoms at days 4 to 14 ‐ Co‐treatment with antibiotics · patients with acute sinusitis

Oral corticosteroids may leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (low certainty).

1 finding from 1 review