Limitations in activities of daily living at 1 year ‐ not reported · people with nerve damage (< 6 months' duration) in leprosy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Limitations in participation at 1 year ‐ not reported · people with nerve damage (< 6 months' duration) in leprosy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events Assessed as: occurrence of one or more major adverse events requiring withdrawal of treatment · people with nerve damage (< 6 months' duration) in leprosy
Corticosteroids showed no clear difference in adverse events Assessed as: occurrence of one or more major adverse… compared with placebo (moderate certainty).
1 finding from 1 review
1Small sample size. · people with nerve damage (< 6 months' duration) in leprosy
1 finding from 1 review
no estimate extracted
1 participants
GRADE not reported
Improvement in sensory nerve function at 1 year · people with nerve damage (6 to 24 months' duration) in leprosy
Corticosteroids showed no clear difference in improvement in sensory nerve function at 1 year compared with placebo (moderate certainty).
1 finding from 1 review
Improvement in motor nerve function at 1 year · people with nerve damage (6 to 24 months' duration) in leprosy
1 finding from 1 review
Number of children with clinical adverse event: vertigo · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
Corticosteroids showed no clear difference in vertigo compared with placebo (low certainty).
1 finding from 1 review
Dizziness Handicap Inventory score · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
1 finding from 1 review
Caloric extent of recovery (improvement as a % in lateralisation of electronystagmography on caloric testing) · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
2 findings from 1 review
Complete caloric recovery · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
Corticosteroids may leads to higher complete caloric recovery compared with placebo (low certainty).
2 findings from 1 review
Adverse effects · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
1 finding from 1 review
Mode of delivery (risk for either assisted or cesarean delivery) · pregnant women
Topical corticosteroids may leads to higher mode of delivery (risk for either assisted or cesarean delivery) compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 1.04
9904 participants
Low
Congenital abnormality · pregnant women
Topical corticosteroids may leads to lower congenital abnormality compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.82
9433 participants
Low
Orofacial cleft · pregnant women
Topical corticosteroids may leads to higher orofacial cleft compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 1.12
40605 participants
Low
Low birthweight · pregnant women
It is very uncertain whether topical corticosteroids changes low birth weight compared with no topical corticosteroids (very low certainty).
1 finding from 1 review
RR 1.08
59419 participants
Very low
Preterm birth · pregnant women
Topical corticosteroids may leads to lower preterm delivery compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.93
59419 participants
Low
Foetal death · pregnant women
It is very uncertain whether topical corticosteroids changes foetal death compared with no topical corticosteroids (very low certainty).
1 finding from 1 review
RR 1.02
63885 participants
Very low
Low Apgar score · pregnant women
Topical corticosteroids may leads to lower low Apgar score compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.84
9220 participants
Low
Clinical improvement (dichotomous) · active EoE patients
Corticosteroids may leads to higher clinical improvement (dichotomous) compared with placebo (low certainty).
1 finding from 1 review
Histological improvement (dichotomous) · inactive EoE patients
Corticosteroids probably leads to higher histological improvement (dichotomous) compared with placebo (moderate certainty).
1 finding from 1 review