Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Neonatal

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No studies found 3 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 1 · 16.7%High 0 · 0%

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Neonatal mortality · neonates with fast breathing alone

Comparison 2: 7 days oral amoxicillin showed no clear difference in neonatal mortality compared with 7 days injectable benzylpenicillin + injectable gentamicin (low certainty).

1 finding from 1 review

Community‐based antibiotic delivery for possible serious bacterial infections in neonates in low‐ and middle‐income… 2019 · Cochrane Headline outcomes only
RR 0.99 [0.2, 4.91]
1 study · 1406 participants
Low

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Early neonatal mortality · neonates with fast breathing alone

The review found no eligible studies for this question.

1 finding from 1 review

Community‐based antibiotic delivery for possible serious bacterial infections in neonates in low‐ and middle‐income… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Late neonatal mortality · neonates with fast breathing alone

The review found no eligible studies for this question.

1 finding from 1 review

Community‐based antibiotic delivery for possible serious bacterial infections in neonates in low‐ and middle‐income… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Sepsis‐specific neonatal mortality · neonates with fast breathing alone

The review found no eligible studies for this question.

1 finding from 1 review

Community‐based antibiotic delivery for possible serious bacterial infections in neonates in low‐ and middle‐income… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Treatment failure · neonates with fast breathing alone

Comparison 2: 7 days oral amoxicillin showed no clear difference in treatment failure compared with 7 days injectable benzylpenicillin + injectable gentamicin (low certainty).

1 finding from 1 review

Community‐based antibiotic delivery for possible serious bacterial infections in neonates in low‐ and middle‐income… 2019 · Cochrane Headline outcomes only
RR 0.83 [0.68, 1.01]
1 study · 1406 participants
Low

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Adverse events · neonates with fast breathing alone

1 finding from 1 review

Community‐based antibiotic delivery for possible serious bacterial infections in neonates in low‐ and middle‐income… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1406 participants
Moderate