Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 20%Low 5 · 50%Moderate 3 · 30%High 0 · 0%

Comparison 13: SSRIs vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults with SAnD

It is very uncertain whether comparison 13: SSRIs changes global Impressions scale change item (CGI‐I or similar): no. of… compared with placebo (very low certainty).

1 finding from 1 review

Comparison 13: SSRIs vs placebo

Clinical Global Impressions scale change item (CGI‐I): no. of responders (long term) Post‐treatment: 1‐4 months · adults with SAnD

Comparison 13: SSRIs may leads to higher clinical Global Impressions scale change item (CGI‐I): no. of… compared with placebo (low certainty).

1 finding from 1 review

Comparison 13: SSRIs vs placebo

Dropouts due to adverse events · adults with SAnD

It is very uncertain whether comparison 13: SSRIs changes dropouts due to adverse events (long term) Post‐treatment: 1‐4 months compared with placebo (very low certainty).

1 finding from 1 review

Comparison 13: SSRIs vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults (aged 18‐85)

Comparison 6: SSRIs probably leads to lower treatment efficacy ‐ treatment response, as measured by the Global… compared with placebo (moderate certainty).

1 finding from 1 review