Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 1 · 14.3%Very low 2 · 28.6%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 0.99 [0.62, 1.59]
1 study · 327 participants
Low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Adverse event: Death · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in adverse event: Death compared with standard care (low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 0.6 [0.2, 1.76]
4 studies · 603 participants
Low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Alcohol use Estimated daily consumption in previous month · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
GRADE not reported

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Drug (non‐alcohol) use Polydrug consumption levels measured by Opiate Treatment Index (OT) · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Relapse · people with both severe mental illness and substance misuse

It is very uncertain whether cognitive behavioural therapy + motivational interviewing changes relapse:* Relapse at 3 months after 9 months of treatment compared with standard care (very low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 0.5 [0.24, 1.04]
1 study · 36 participants
Very low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Global state: average score(GAF scale of 1 ‐ 100) · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 445 participants
Very low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Quality of life / life satisfaction: Brief Quality of Life Scale · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 110 participants
Low