Findings

What do systematic reviews say?

5 questions · 6 findings · 1 reviews · Epilepsy

No studies found 2 · 33.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 66.7%Moderate 0 · 0%High 0 · 0%

Time on allocated treatment (retention time) · people with focal or generalized seizures

The review found no eligible studies for this question.

1 finding from 1 review

Clobazam monotherapy for focal or generalized seizures 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Retention [ · people with focal or generalized seizures

Clobazam showed no clear difference in retention at 12 months compared with carbamazepine (low certainty).

1 finding from 1 review

Clobazam monotherapy for focal or generalized seizures 2018 · Cochrane Headline outcomes only
RR 0.83 [0.61, 1.12]
1 study · 115 participants
Low

Seizure freedom · people with focal or generalized seizures

Clobazam showed no clear difference in seizure freedom at 4 weeks compared with carbamazepine (low certainty).

2 findings from 1 review

Clobazam monotherapy for focal or generalized seizures 2018 · Cochrane Headline outcomes only
RR 0.85 [0.55, 1.32]
1 study · 43 participants
Low
Clobazam monotherapy for focal or generalized seizures 2018 · Cochrane Headline outcomes only
RR 0.95 [0.66, 1.36]
1 study · 43 participants
Low

50% responder rate · people with focal or generalized seizures

Clobazam showed no clear difference in 50% responder rate compared with carbamazepine (low certainty).

1 finding from 1 review

Clobazam monotherapy for focal or generalized seizures 2018 · Cochrane Headline outcomes only
RR 1.18 [0.94, 1.48]
1 study · 43 participants
Low

Adverse effects requiring withdrawal/discontinuation of study medication · people with focal or generalized seizures

The review found no eligible studies for this question.

1 finding from 1 review

Clobazam monotherapy for focal or generalized seizures 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found