What do systematic reviews say?

Class III antiarrhythmics vs control

The review found no eligible studies for this question.

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Class III antiarrhythmics vs control

Class III antiarrhythmics showed no clear difference in recurrence of atrial tachyarrhythmias compared with control (low certainty).

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  RR 0.82 [0.62, 1.09]
  2 studies · 318 participants
  Low

Class III antiarrhythmics vs control

It is very uncertain whether class III antiarrhythmics changes adverse events: thromboembolic events compared with control (very low certainty).

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  Peto OR 0.96 [0.06, 15.5]
  1 study · 212 participants
  Very low

Class III antiarrhythmics vs control

The review found no eligible studies for this question.

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Class III antiarrhythmics vs control

The review found no eligible studies for this question.

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Class III antiarrhythmics vs control

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 participants
  GRADE not reported

Class III antiarrhythmics vs control

It is very uncertain whether class III antiarrhythmics changes all‐cause mortality compared with control (very low certainty).

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  Peto OR 0.13 [0, 6.57]
  1 study · 212 participants
  Very low

Class III antiarrhythmics vs control

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 participants
  GRADE not reported

Class I and/or III antiarrhythmics vs control

The review found no eligible studies for this question.

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Class I and/or III antiarrhythmics vs control

Class I and/or III antiarrhythmics probably leads to lower recurrence of atrial tachyarrhythmias compared with control (moderate certainty).

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  RR 0.85 [0.78, 0.93]
  5 studies · 2591 participants
  Moderate

Class I and/or III antiarrhythmics vs control

It is very uncertain whether class I and/or III antiarrhythmics changes adverse events: thromboembolic events compared with control (very low certainty).

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  Peto OR 0.96 [0.06, 15.5]
  1 study · 212 participants
  Very low

Class I and/or III antiarrhythmics vs control

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 participants
  GRADE not reported

Class I and/or III antiarrhythmics vs control

The review found no eligible studies for this question.

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Class I and/or III antiarrhythmics vs control

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 participants
  GRADE not reported

Class I and/or III antiarrhythmics vs control

Class I and/or III antiarrhythmics showed no clear difference in all‐cause mortality compared with control (low certainty).

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  Peto OR 1 [0.06, 16.24]
  1 study · 90 participants
  Low

Class I and/or III antiarrhythmics vs control

• Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 participants
  GRADE not reported