What do systematic reviews say?

Citrate vs unfractionated heparin

Citrate showed no clear difference in death at 28 days compared with unfractionated heparin (moderate certainty).

• Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement… 2020 · Cochrane Headline outcomes only
  RR 1.06 [0.86, 1.3]
  5 studies · 462 participants
  Moderate