Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 2 reviews

No studies found 2 · 20%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 30%Moderate 5 · 50%High 0 · 0%

Ciclopirox vs placebo

Side effects (combined for face and scalp) Self report · patients with seborrhoeic dermatitis

Ciclopirox showed no clear difference in side effects (combined for face and scalp) Self reported compared with placebo (moderate certainty).

1 finding from 1 review

Ciclopirox vs placebo

Failure to achieve complete resolution (combined for face and scalp) Clinical assessment · patients with seborrhoeic dermatitis

Ciclopirox probably leads to lower failure to achieve complete resolution (combined for face and scalp)… compared with placebo (moderate certainty).

1 finding from 1 review

Ciclopirox 8% lacquer vs vehicle

Adverse events (directly related to treatment, collected over the course of the studies; they are not measured/reported for specific time points) · People with fungal infections of the toenails

Ciclopirox 8% lacquer showed no clear difference in adverse events (directly related to treatment, collected over the… compared with vehicle (low certainty).

1 finding from 1 review

P‐3051 (ciclopirox 8% hydrolacquer) vs comparators

Adverse events (collected over the course of the studies; they are not measured/reported for specific time points) · People with fungal infections of the toenails

P‐3051 (ciclopirox 8% hydrolacquer) showed no clear difference in adverse events (collected over the course of the studies; they are… compared with comparators (low certainty).

1 finding from 1 review