Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

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No studies found 4 · 66.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%

Chloral hydrate oral (50 mg/kg) vs melatonin oral

Proportion of children who successfully completed neurodiagnostic procedure without interruption by the child awakening · children undergoing neurodiagnostic procedures

The review found no eligible studies for this question.

1 finding from 1 review

Chloral hydrate as a sedating agent for neurodiagnostic procedures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Chloral hydrate oral (50 mg/kg) vs melatonin oral

Proportion of children who required a further dose of either the same sedative agent or the addition of a different sedative agent · children undergoing neurodiagnostic procedures

The review found no eligible studies for this question.

1 finding from 1 review

Chloral hydrate as a sedating agent for neurodiagnostic procedures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Chloral hydrate oral (50 mg/kg) vs melatonin oral

Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures

The review found no eligible studies for this question.

1 finding from 1 review

Chloral hydrate as a sedating agent for neurodiagnostic procedures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Chloral hydrate oral (50 mg/kg) vs melatonin oral

Proportion of children who had sedation failure or inadequate level of sedation · children undergoing neurodiagnostic procedures

The review found no eligible studies for this question.

1 finding from 1 review

Chloral hydrate as a sedating agent for neurodiagnostic procedures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Chloral hydrate oral (50 mg/kg) vs melatonin oral

EEG sedative‐induced artefact · children undergoing neurodiagnostic procedures

Chloral hydrate oral (50 mg/kg) may leads to lower EEG sedative‐induced artefact compared with melatonin oral (low certainty).

1 finding from 1 review

Chloral hydrate as a sedating agent for neurodiagnostic procedures in children 2021 · Cochrane Headline outcomes only
RR 0.33 [0.14, 0.82]
1 study · 348 participants
Low

Chloral hydrate oral (50 mg/kg) vs melatonin oral

Number of children with clinical adverse events (any) · children undergoing neurodiagnostic procedures

Chloral hydrate oral (50 mg/kg) showed no clear difference in number of children with clinical adverse events (any) compared with melatonin oral (low certainty).

1 finding from 1 review

Chloral hydrate as a sedating agent for neurodiagnostic procedures in children 2021 · Cochrane Headline outcomes only
RR 1 [0.25, 3.93]
1 study · 348 participants
Low