Proportion of children who had sedation failure after 1 dose of sedative agent · children undergoing neurodiagnostic procedures
Chloral hydrate oral (100 mg/kg or 75 mg/kg) showed no clear difference in proportion of children who had sedation failure after 1 dose of… compared with midazolam (intranasal 0.2 mg/kg or oral 0.5 mg/kg) (low certainty).
1 finding from 1 review
Sedation duration (minutes) · children undergoing neurodiagnostic procedures
1 finding from 1 review
EEG sedative‐induced artefact · children undergoing neurodiagnostic procedures
Chloral hydrate oral (100 mg/kg or 75 mg/kg) leads to lower EEG sedative‐induced artefact compared with midazolam (intranasal 0.2 mg/kg or oral 0.5 mg/kg) (high certainty).
1 finding from 1 review
Number of children with clinical adverse events (any) · children undergoing neurodiagnostic procedures
Chloral hydrate oral (100 mg/kg or 75 mg/kg) showed no clear difference in number of children with clinical adverse events (any) compared with midazolam (intranasal 0.2 mg/kg or oral 0.5 mg/kg) (low certainty).
1 finding from 1 review
Proportion of children who had sedation failure after 1 dose of sedative agent · children undergoing neurodiagnostic procedures
Chloral hydrate oral (75 mg/kg) may leads to higher proportion of children who had sedation failure after 1 dose of… compared with pentobarbital intravenous (5 mg/kg) (low certainty).
1 finding from 1 review
Proportion of children who had sedation failure after 2 doses of sedative agent (same or different) · children undergoing neurodiagnostic procedures
It is very uncertain whether chloral hydrate oral (75 mg/kg) changes proportion of children who had sedation failure after 2 doses of… compared with pentobarbital intravenous (5 mg/kg) (very low certainty).
1 finding from 1 review
Non‐interpretable neuroimaging finding · children undergoing neurodiagnostic procedures
It is very uncertain whether chloral hydrate oral (75 mg/kg) changes non‐interpretable neuroimaging finding compared with pentobarbital intravenous (5 mg/kg) (very low certainty).
1 finding from 1 review
Number of children with clinical adverse event: oxygen desaturation · children undergoing neurodiagnostic procedures
It is very uncertain whether chloral hydrate oral (75 mg/kg) changes number of children with clinical adverse event: oxygen desaturation compared with pentobarbital intravenous (5 mg/kg) (very low certainty).
1 finding from 1 review
Proportion of children who successfully completed neurodiagnostic procedure without interruption by the child awakening · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of children who required a further dose of either the same sedative agent or the addition of a different sedative agent · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Proportion of children who successfully completed neurodiagnostic procedure without interruption by the child awakening · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of children who required a further dose of either the same sedative agent or the addition of a different sedative agent · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Proportion of children who had sedation failure or inadequate level of sedation · children undergoing neurodiagnostic procedures
Chloral hydrate oral (50 mg/kg or 100 mg/kg) showed no clear difference in proportion of children who had sedation failure or inadequate level… compared with dexmedetomidine oral (2 µg/kg or 3 µg/kg) (moderate certainty).
1 finding from 1 review
Sedation duration (minutes) · children undergoing neurodiagnostic procedures
1 finding from 1 review
Number of children with clinical adverse events (any) · children undergoing neurodiagnostic procedures
Chloral hydrate oral (50 mg/kg or 100 mg/kg) may leads to higher number of children with clinical adverse events (any) compared with dexmedetomidine oral (2 µg/kg or 3 µg/kg) (low certainty).
1 finding from 1 review
Proportion of children who successfully completed neurodiagnostic procedure without interruption by the child awakening · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of children who required a further dose of either the same sedative agent or the addition of a different sedative agent · children undergoing neurodiagnostic procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to adequate sedation (minutes or as measured by specific validated scales such as the Ramsay Sedation Score) · children undergoing neurodiagnostic procedures
1 finding from 1 review