Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Chloral hydrate oral (100 mg/kg or 75 mg/kg) vs midazolam

Number of children with clinical adverse events (any) · children undergoing neurodiagnostic procedures

Chloral hydrate oral (100 mg/kg or 75 mg/kg) showed no clear difference in number of children with clinical adverse events (any) compared with midazolam (intranasal 0.2 mg/kg or oral 0.5 mg/kg) (low certainty).

1 finding from 1 review

Chloral hydrate oral (50 mg/kg or 100 mg/kg) vs dexmedetomidine oral (2 µg/kg or 3 µg/kg)

Number of children with clinical adverse events (any) · children undergoing neurodiagnostic procedures

Chloral hydrate oral (50 mg/kg or 100 mg/kg) may leads to higher number of children with clinical adverse events (any) compared with dexmedetomidine oral (2 µg/kg or 3 µg/kg) (low certainty).

1 finding from 1 review