Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Pregnancy and Childbirth

No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 3 · 42.9%High 0 · 0%

Maternal infection or inflammation · women with singleton pregnancies at risk of cervical insufficiency

Cervical pessary showed no clear difference in maternal infection or inflammation compared with vaginal progesterone (moderate certainty).

1 finding from 1 review

Cervical pessary for preventing preterm birth in singleton pregnancies 2022 · Cochrane Headline outcomes only
RR 0.95 [0.81, 1.12]
2 studies · 265 participants
Moderate

Neonatal/paediatric care unit admission · women with singleton pregnancies at risk of cervical insufficiency

Cervical pessary showed no clear difference in neonatal/paediatric care unit admission compared with vaginal progesterone (low certainty).

1 finding from 1 review

Cervical pessary for preventing preterm birth in singleton pregnancies 2022 · Cochrane Headline outcomes only
RR 0.98 [0.49, 1.98]
1 study · 254 participants
Low

Fetal/infant mortality · women with singleton pregnancies at risk of cervical insufficiency

Cervical pessary showed no clear difference in fetal/infant mortality compared with vaginal progesterone (low certainty).

1 finding from 1 review

Cervical pessary for preventing preterm birth in singleton pregnancies 2022 · Cochrane Headline outcomes only
RR 1.97 [0.5, 7.7]
2 studies · 265 participants
Low

Harm to offspring from the intervention · women with singleton pregnancies at risk of cervical insufficiency

1 finding from 1 review

Cervical pessary for preventing preterm birth in singleton pregnancies 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 11 participants
Low

Birthweight (g) · women with singleton pregnancies at risk of cervical insufficiency

The review found no eligible studies for this question.

1 finding from 1 review

Cervical pessary for preventing preterm birth in singleton pregnancies 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Preterm birth less than 34 weeks' gestation · women with singleton pregnancies at risk of cervical insufficiency

Cervical pessary showed no clear difference in delivery before 34 weeks' gestation compared with vaginal progesterone (moderate certainty).

1 finding from 1 review

Cervical pessary for preventing preterm birth in singleton pregnancies 2022 · Cochrane Headline outcomes only
RR 0.72 [0.52, 1.02]
3 studies · 1126 participants
Moderate

Preterm birth · women with singleton pregnancies at risk of cervical insufficiency

Cervical pessary showed no clear difference in delivery before 37 weeks' gestation compared with vaginal progesterone (moderate certainty).

1 finding from 1 review

Cervical pessary for preventing preterm birth in singleton pregnancies 2022 · Cochrane Headline outcomes only
RR 0.89 [0.73, 1.09]
3 studies · 1126 participants
Moderate