Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Short‐term serious adverse events · patients with rheumatoid arthritis

Celecoxib showed no clear difference in short‐term serious adverse events compared with traditional NSAIDs (low certainty).

1 finding from 1 review

Celecoxib for rheumatoid arthritis 2017 · Cochrane Headline outcomes only
Peto OR 0.71 [0.39, 1.28]
5 studies · 2154 participants
Low

Number of participants experiencing any serious adverse events · patients with osteoarthritis

It is very uncertain whether celecoxib changes number experiencing any serious adverse events compared with tNSAIDs (very low certainty).

1 finding from 1 review

Celecoxib for osteoarthritis 2017 · Cochrane Headline outcomes only
Peto OR 0.92 [0.66, 1.28]
5 studies · 2404 participants
Very low