Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Infectious Diseases

No studies found 3 · 42.9%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%

Relapse · children under 18 years of age with enteric fever

It is very uncertain whether ceftriaxone changes relapse compared with azithromycin (very low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
RR 10.05 [1.93, 52.38]
3 studies · 185 participants
Very low

Time to defervescence · children under 18 years of age with enteric fever

Ceftriaxone showed no clear difference in time to defervescence compared with azithromycin (low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 196 participants
Low

Length of hospital stay · children under 18 years of age with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Convalescent faecal carriage · children under 18 years of age with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Serious adverse events · children under 18 years of age with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clinical failure · children under 18 years of age with enteric fever

Ceftriaxone showed no clear difference in clinical failure compared with azithromycin (low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
RR 0.42 [0.11, 1.57]
3 studies · 196 participants
Low

Microbiological failure · children under 18 years of age with enteric fever

It is very uncertain whether ceftriaxone changes microbiological failure compared with azithromycin (very low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
RR 1.95 [0.36, 10.64]
3 studies · 196 participants
Very low