Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews · All outcomes

No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Cariogram multivariable caries-risk model (including modified/reduced-predictor versions) vs Alternative prediction model(s) within the same study, or no formal comparator (models compared descriptively; no between-model statistical test)

Predictive performance of the Cariogram for caries increment (positive likelihood ratio, LR+) · Children/adolescents (coronal caries) and older adults (root caries); populations from areas with varying caries risk

Modified Cariogram models showed modest positive likelihood ratios (LR+ ~1.1-3.8) for predicting caries increment, generally below the useful threshold; no pooled estimate; ungraded.

1 finding from 1 review
  • Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomes
    Follow-up >=1 year (included studies 1-5 years) · Oral health care; children/adolescents and older adults; multiple countries · Model validation studies
    Six validation studies (5 coronal, 1 root) evaluated modified Cariogram models (not the original model per se). Review-stated LR+ range 1.1-3.8 (with one exception). LR+ was not substantially changed by excluding the…
    6 studies
    GRADE not reported

Cariogram multivariable caries-risk model (including modified/reduced-predictor versions) vs Alternative prediction model(s) within the same study, or no formal comparator (models compared descriptively; no between-model statistical test)

Predictive performance of the Cariogram for caries increment (negative likelihood ratio, LR-) · Children/adolescents (coronal caries) and older adults (root caries); populations from areas with varying caries risk

Modified Cariogram models showed negative likelihood ratios of about 0.5-0.61, above the useful rule-out threshold; no pooled estimate; ungraded.

1 finding from 1 review
  • Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomes
    Follow-up >=1 year (included studies 1-5 years) · Oral health care; children/adolescents and older adults; multiple countries · Model validation studies
    Review-stated LR- range 0.5-0.61 across the Cariogram validation models (with one exception). Model performance was largely unaffected by removing the predictors mutans streptococci in saliva, saliva secretion and…
    6 studies
    GRADE not reported