Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Oral medicine and oral cancer

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No studies found 0 · 0%GRADE not reported 5 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Carboxymethylcellulose (CMC) spray vs Placebo (spray base without CMC / water)

Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…

1 finding from 1 review

Interventions for the management of dry mouth: topical therapies 2011 · Cochrane All outcomes
Donatsky 1982 (crossover, n=15, Sjogren's syndrome): CMC spray had a similar effect on oral dryness to the spray base, but was more effective than water. Paired crossover data not presented; effect size not estimable.
1 study · 15 participants
GRADE not reported

Carboxymethylcellulose (CMC) spray vs Salinum linseed oil spray

Oral health (plaque and gingival indices) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…

1 finding from 1 review

Interventions for the management of dry mouth: topical therapies 2011 · Cochrane All outcomes
Mean plaque and gingival indices were reduced during the Salinum (linseed) period; incomplete comparative data.
1 study · 20 participants
GRADE not reported

Carboxymethylcellulose (CMC) spray vs Salinum linseed oil spray

Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…

1 finding from 1 review

Interventions for the management of dry mouth: topical therapies 2011 · Cochrane All outcomes
Andersson 1995 (crossover, n=20): more participants experienced a reduction in oral dryness with linseed (Salinum) spray than with CMC spray; crossover data not accounted for, no usable estimate.
1 study · 20 participants
GRADE not reported

Carboxymethylcellulose (CMC) spray vs Salinum linseed oil spray

Patient preference · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…

1 finding from 1 review

Interventions for the management of dry mouth: topical therapies 2011 · Cochrane All outcomes
Statistically significant preference for linseed spray: of 17 with a preference, more favoured linseed (Chi2 4.77, df=1; P = 0.029); 3 expressed no preference.
1 study · 20 participants
GRADE not reported

Carboxymethylcellulose (CMC) spray vs Placebo (spray base without CMC / water)

Patient preference · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…

1 finding from 1 review

Interventions for the management of dry mouth: topical therapies 2011 · Cochrane All outcomes
Patient preference evenly split between CMC spray and spray base.
1 study · 15 participants
GRADE not reported