Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Epilepsy

Sort:Best matchNewest Highest certainty Download CSV

No studies found 3 · 75%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 1 · 25%

Cannabidiol (10 mg/kg and 20 mg/kg) plus ASMs vs placebo plus ASMs

Seizure freedom · Lennox‐Gastaut syndrome, any age

The review found no eligible studies for this question.

1 finding from 1 review

Anti‐seizure medications for Lennox‐Gastaut syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cannabidiol (10 mg/kg and 20 mg/kg) plus ASMs vs placebo plus ASMs

Number of participants with ≥ 75% reduction in all seizures · Lennox‐Gastaut syndrome, any age

The review found no eligible studies for this question.

1 finding from 1 review

Anti‐seizure medications for Lennox‐Gastaut syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cannabidiol (10 mg/kg and 20 mg/kg) plus ASMs vs placebo plus ASMs

50% or greater reduction in seizure frequency · Lennox‐Gastaut syndrome, any age

The review found no eligible studies for this question.

1 finding from 1 review

Anti‐seizure medications for Lennox‐Gastaut syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cannabidiol (10 mg/kg and 20 mg/kg) plus ASMs vs placebo plus ASMs

Number of participants with adverse events leading to study discontinuation · Lennox‐Gastaut syndrome, any age

Cannabidiol (10 mg/kg and 20 mg/kg) plus ASMs leads to higher number of participants with adverse events leading to study… compared with placebo plus ASMs (high certainty).

1 finding from 1 review

Anti‐seizure medications for Lennox‐Gastaut syndrome 2021 · Cochrane Headline outcomes only
RR 6.62 [1.56, 28.15]
2 studies · 396 participants
High