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Evidence found and GRADE certainty

3 questions · 5 findings · 1 reviews · Dental caries

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 20%Moderate 4 · 80%High 0 · 0%

Calcium phosphate agent (e.g., CPP-ACP, Ca/P-PILP, niobophosphate) vs Fluoride agent (e.g., NaF/SDF/KF/CaF2)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Calcium Phosphate vs Fluorine showed no significant difference in 24 h bond strength (MD 2.140, 95% CI -1.506 to 5.787; Moderate certainty).

2 findings from 1 review

Calcium phosphate agent (e.g., CPP-ACP, Ca/P-PILP, niobophosphate) vs Calcium-based agent

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Etch-and-Rinse adhesive + chemical ACAD protocol network, Calcium Phosphate vs Calcium showed no significant difference in 24 h bond strength (MD 0.596, 95% CI -7.289 to 8.482; Low certainty).

2 findings from 1 review

Calcium phosphate agent (e.g., CPP-ACP, Ca/P-PILP, niobophosphate) vs No biomimetic remineralization (control)

Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)

In the Self-Etch adhesive + chemical ACAD protocol network, Calcium Phosphate vs Control showed no significant difference in 24 h bond strength (MD 1.539, 95% CI -1.738 to 4.817; Moderate certainty).

1 finding from 1 review