nCaF2 primer vs Control Transbond primer
White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)
A single small split-mouth RCT found the nCaF2-containing primer reduced demineralization (DIAGNOdent) but showed no significant clinical white spot lesion difference at debonding (ungraded).
1 finding from 1 review
- Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed Orthodontic… 2024 All outcomes1, 3 and 6 months (during treatment to debonding) · Orthodontic clinical practice (in-vivo human clinical trials); adolescents and adultsAl Tuma 2023 (1 split-mouth RCT, 31 patients / 310 teeth): DIAGNOdent scores significantly favored the nCaF2 primer at 1, 3 and 6 months (p=0.000) and S. mutans count differed at 1 month; no significant difference in…1 study · 31 participantsGRADE not reported