Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Calcineurin inhibitor (CNI) avoidance and late CNI withdrawal vs standard dose CNI

Acute rejection: avoidance · kidney transplant recipients

Calcineurin inhibitor (CNI) avoidance and late CNI withdrawal showed no clear difference in acute rejection: avoidance compared with standard dose CNI (low certainty).

1 finding from 1 review

Calcineurin inhibitor withdrawal or tapering for kidney transplant recipients 2017 · Cochrane Headline outcomes only
RR 2.16 [0.85, 5.49]
3 studies · 238 participants
Low

Calcineurin inhibitor (CNI) avoidance and late withdrawal with mammalian target of rapamycin inhibitor (mTORi) vs standard dose CNI

Acute rejection: avoidance · kidney transplant recipients

Calcineurin inhibitor (CNI) avoidance and late withdrawal with… showed no clear difference in acute rejection: avoidance compared with standard dose CNI (moderate certainty).

1 finding from 1 review

Calcineurin inhibitor withdrawal or tapering for kidney transplant recipients 2017 · Cochrane Headline outcomes only
RR 1.27 [0.98, 1.65]
11 studies · 1844 participants
Moderate