Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Calcineurin inhibitor vs IV cyclophosphamide

Partial remission ( · idiopathic steroid‐resistant nephrotic syndrome in children

It is very uncertain whether calcineurin inhibitor changes treatment response at 3 to 6 months: partial remission compared with IV cyclophosphamide (very low certainty).

1 finding from 1 review

Interventions for idiopathic steroid‐resistant nephrotic syndrome in children 2019 · Cochrane Headline outcomes only
RR 1.68 [0.43, 6.56]
2 studies · 156 participants
Very low

Calcineurin inhibitor vs IV cyclophosphamide

Complete or partial remission · idiopathic steroid‐resistant nephrotic syndrome in children

Calcineurin inhibitor may leads to higher treatment response at 3 to 6 months: complete or partial remission compared with IV cyclophosphamide (low certainty).

1 finding from 1 review

Interventions for idiopathic steroid‐resistant nephrotic syndrome in children 2019 · Cochrane Headline outcomes only
RR 1.98 [1.25, 3.13]
2 studies · 156 participants
Low