CT + TT genotype (T-allele carriers) of AMELX rs17878486 vs CC genotype of AMELX rs17878486
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
The CT + TT genotype (T-allele carriers) of AMELX rs17878486 was associated with increased dental caries risk (CT + TT vs CC model: OR 5.72, 95% CI 2.83-11.59) after excluding the outlier study (Ergoz 2014); certainty not graded.
9 findings from 1 review
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · Sensitivity: study Ergoz 2014 excludedOR 5.72 [2.83, 11.59]3 studiesGRADE not reported
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · Control group: Caries-freeOR 2.03 [0.10, 42.44]2 studiesGRADE not reported
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · OverallOR 2.30 [0.51, 10.33]4 studies · 442 participantsGRADE not reported
Show 6 more findings
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · Control group: Low cariesOR 3.43 [1.21, 9.75]2 studiesGRADE not reported
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · Ethnicity: AsianOR 0.89 [0.04, 22.53]1 studyGRADE not reported
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · Ethnicity: MixedOR 4.03 [1.27, 12.75]1 studyGRADE not reported
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · Age group: ChildrenOR 2.65 [0.49, 14.35]3 studiesGRADE not reported
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · Age group: AdultsOR 0.89 [0.04, 22.53]1 studyGRADE not reported
- Association of LTF, ENAM, and AMELX polymorphisms with dental caries susceptibility: a meta-analysis. 2020 All outcomesCase-control genetic association studies (multiple countries) · Ethnicity: CaucasianOR 2.03 [0.10, 42.44]2 studiesGRADE not reported