Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 6 findings · 1 reviews · Oral Health

No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 5 · 83.3%High 0 · 0%

COE with vital rinsing (toluidine blue/tolonium chloride) vs Conventional oral examination (COE) alone

Specificity · Oral cavity cancer or potentially malignant disorder symptom-free individuals with tobacco habits
2 findings from 1 review

COE with vital rinsing (toluidine blue/tolonium chloride) vs Conventional oral examination (COE) alone

Detection rate of oral pre-malignant and malignant lesions after referral (COE+vital rinsing vs COE alone) · Oral cavity cancer or potentially malignant disorder symptom-free individuals with tobacco habits

COE with vital rinsing (toluidine blue/tolonium chloride) showed no clear difference in detection rate of oral pre-malignant and malignant lesions after… compared with conventional oral examination (COE) alone (moderate certainty).

1 finding from 1 review

COE with vital rinsing (toluidine blue/tolonium chloride) vs Reference standard: examination and clinical evaluation by a physician/clinician with specialist knowledge or training (long-term follow-up accepted for those screened negative)

Outcome not reported · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…

The review found no eligible studies for this question.

1 finding from 1 review