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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews

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No studies found 3 · 42.9%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

CLOZAPINE + ZIPRASIDONE vs CLOZAPINE + QUETIAPINE (Wen 2015)

Clinical response: no clinically significant response in mental state: ≥ 50% reduction in PANSS total score Medium term (12 weeks) · people with treatment‐resistant schizophrenia

CLOZAPINE + ZIPRASIDONE may leads to lower clinical response: no clinically significant response in mental… compared with CLOZAPINE + QUETIAPINE (Wen 2015) (low certainty).

1 finding from 1 review

CLOZAPINE + ZIPRASIDONE vs CLOZAPINE + QUETIAPINE (Wen 2015)

Leaving the study early · people with treatment‐resistant schizophrenia

It is very uncertain whether CLOZAPINE + ZIPRASIDONE changes leaving the study early: acceptability of treatment ‐ as measured by… compared with CLOZAPINE + QUETIAPINE (Wen 2015) (very low certainty).

1 finding from 1 review

CLOZAPINE + ZIPRASIDONE vs CLOZAPINE + QUETIAPINE (Wen 2015)

Quality of life/satisfaction with care for either recipients of care or carers: significant change in quality of life/satisfaction · people with treatment‐resistant schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review