Findings

What do systematic reviews say?

9 questions · 9 findings · 1 reviews · Kidney and Transplant

No studies found 2 · 22.2%GRADE not reported 0 · 0%Very low 3 · 33.3%Low 3 · 33.3%Moderate 1 · 11.1%High 0 · 0%

Death (any cause) ( · heart failure with chronic kidney disease

CHRONIC: Beta‐blockers probably leads to lower death (any cause) ( compared with placebo (moderate certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.69 [0.6, 0.79]
4 studies · 3136 participants
Moderate

All cardiovascular death · heart failure with chronic kidney disease

CHRONIC: Beta‐blockers may leads to lower cardiovascular death ( compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.53 [0.35, 0.81]
3 studies · 2287 participants
Low

Hospitalisation (any cause) · heart failure with chronic kidney disease

CHRONIC: Beta‐blockers showed no clear difference in hospitalisation (any cause) compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.75 [0.52, 1.08]
2 studies · 1583 participants
Low

Heart failure hospitalisation (RR) · heart failure with chronic kidney disease

CHRONIC: Beta‐blockers showed no clear difference in heart failure hospitalisation ( compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.67 [0.43, 1.05]
3 studies · 2287 participants
Low

Worsening heart failure · heart failure with chronic kidney disease

It is very uncertain whether CHRONIC: Beta‐blockers changes worsening heart failure compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 1.36 [0.58, 3.2]
1 study · 704 participants
Very low

Worsening kidney function · heart failure with chronic kidney disease

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 704 participants
Very low

Hypotension · heart failure with chronic kidney disease

It is very uncertain whether CHRONIC: Beta‐blockers changes hypotension compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 5.11 [0.25, 106.15]
1 study · 704 participants
Very low

Hyperkalaemia · heart failure with chronic kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Quality of life · heart failure with chronic kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found