Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%

Bupropion plus nicotine replacement therapy (NRT) vs NRT

Smoking cessation · people who smoke

Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in smoking cessation (at least six months of compared with NRT alone (low certainty).

1 finding from 1 review

Antidepressants for smoking cessation 2023 · Cochrane Headline outcomes only
RR 1.17 [0.95, 1.44]
15 studies · 4117 participants
Low

Bupropion plus nicotine replacement therapy (NRT) vs NRT

Serious adverse events · people who smoke

Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in serious adverse events compared with NRT alone (low certainty).

1 finding from 1 review

Antidepressants for smoking cessation 2023 · Cochrane Headline outcomes only
RR 1.52 [0.26, 8.89]
4 studies · 657 participants
Low

Bupropion plus nicotine replacement therapy (NRT) vs NRT

Dropouts due to treatment · people who smoke

Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in dropouts due to treatment compared with NRT alone (low certainty).

1 finding from 1 review

Antidepressants for smoking cessation 2023 · Cochrane Headline outcomes only
RR 1.67 [0.95, 2.92]
3 studies · 737 participants
Low