Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Serious adverse events · Adult patients with active ulcerative colitis

Budesonide showed no clear difference in serious adverse events compared with mesalamine (low certainty).

1 finding from 1 review

Oral budesonide for induction of remission in ulcerative colitis 2015 · Cochrane Headline outcomes only
RR 0.75 [0.17, 3.28]
1 study · 254 participants
Low

Adverse events Gross 2011 · Adult patients with active ulcerative colitis

Budesonide showed no clear difference in adverse events Gross 2011 compared with mesalamine (moderate certainty).

1 finding from 1 review

Oral budesonide for induction of remission in ulcerative colitis 2015 · Cochrane Headline outcomes only
RR 1.05 [0.73, 1.5]
1 study · 343 participants
Moderate

Withdrawals due to adverse events · Patients with active Crohn's disease

Budesonide 9 mg showed no clear difference in withdrawal due to adverse events compared with mesalamine (low certainty).

1 finding from 1 review

Budesonide for induction of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 0.43 [0.18, 1.03]
2 studies · 489 participants
Low