The review found no eligible studies for this question.
Budesonide 3 mg showed no clear difference in induction of clinical remission (CDAI < 150) ‐ 8 weeks compared with placebo (low certainty).
Budesonide 3 mg showed no clear difference in withdrawal due to adverse events compared with placebo (low certainty).
Budesonide 3 mg showed no clear difference in withdrawal due to disease worsening compared with placebo (moderate certainty).
Budesonide 3 mg showed no clear difference in corticosteroid related adverse events compared with placebo (low certainty).
Budesonide 6 mg showed no clear difference in continued remission at 3 months compared with placebo (low certainty).
It is very uncertain whether budesonide 6 mg changes continued remission at 12 months compared with mesalamine 3 g (very low certainty).
Budesonide 3 mg probably leads to higher continued remission at 3 months compared with placebo (moderate certainty).
Budesonide 15 mg probably leads to higher induction of clinical remission (CDAI < 150) ‐ 8 weeks compared with placebo (moderate certainty).
Budesonide 15 mg showed no clear difference in clinical improvement (decrease in CDAI > 100 or total CDAI <= 150) ‐… compared with placebo (low certainty).
Budesonide 15 mg showed no clear difference in withdrawal due to adverse events compared with placebo (low certainty).
Budesonide 15 mg probably leads to lower withdrawal due to disease worsening compared with placebo (moderate certainty).
Budesonide 15 mg showed no clear difference in corticosteroid related adverse events compared with placebo (moderate certainty).
Budesonide 10 mg showed no clear difference in endoscopic improvement compared with prednisolone 40 mg (low certainty).
It is very uncertain whether budesonide 10 mg changes endoscopic remission compared with prednisolone 40 mg (very low certainty).
It is very uncertain whether budesonide 10 mg changes histologic remission compared with prednisolone 40 mg (very low certainty).
It is very uncertain whether budesonide 10 mg changes adverse event ‐ Reduction in plasma cortisol below lower reference… compared with prednisolone 40 mg (very low certainty).
It is very uncertain whether budesonide 10 mg changes study withdrawals compared with prednisolone 40 mg (very low certainty).
It is very uncertain whether budesonide 10 mg changes withdrawal due to adverse event compared with prednisolone 40 mg (very low certainty).