Findings

What do systematic reviews say?

8 questions · 8 findings · 3 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 37.5%Low 5 · 62.5%Moderate 0 · 0%High 0 · 0%

Adverse events · Patients with collagenous colitis

Budesonide showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
RR 1.18 [0.92, 1.51]
5 studies · 290 participants
Low

Adverse events · Patients with collagenous colitis

Budesonide showed no clear difference in adverse events compared with mesalazine (low certainty).

1 finding from 1 review

Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
RR 0.69 [0.43, 1.1]
1 study · 55 participants
Low

Adverse events · patients with active lymphocytic colitis

Budesonide showed no clear difference in adverse events compared with mesalazine (low certainty).

1 finding from 1 review

Interventions for treating lymphocytic colitis 2017 · Cochrane Headline outcomes only
RR 0.67 [0.12, 3.59]
1 study · 42 participants
Low

Serious adverse events · Patients with collagenous colitis

Budesonide showed no clear difference in serious adverse events compared with mesalazine (low certainty).

1 finding from 1 review

Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
RR 0.12 [0.01, 2.21]
1 study · 55 participants
Low

Serious adverse events · Patients with collagenous colitis

It is very uncertain whether budesonide changes serious adverse events compared with placebo (very low certainty).

1 finding from 1 review

Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
RR 1.11 [0.15, 8.01]
4 studies · 175 participants
Very low

Withdrawals due to adverse events · Patients with collagenous colitis

It is very uncertain whether budesonide changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
RR 0.97 [0.43, 2.17]
5 studies · 290 participants
Very low

Withdrawals due to adverse events · Patients with collagenous colitis

Budesonide showed no clear difference in withdrawals due to adverse events compared with mesalazine (low certainty).

1 finding from 1 review

Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
RR 0.09 [0.01, 1.65]
1 study · 55 participants
Low

Side effects or other adverse events · participants at risk of high altitude illness

1 finding from 1 review

Interventions for preventing high altitude illness: Part 1. Commonly‐used classes of drugs 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low