What do systematic reviews say?

Biodentine vs Calcium hydroxide (CH)

Biodentine showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.

• Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes

  6 and 12 months
  RR 0.33 [0.01, 7.72]
  1 study · 62 participants
  GRADE not reported

Biodentine vs Formocresol (FC)

• Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes

  6 months
  No clinical failure in any participant (El Meligy 2016); not estimable
  1 study · 112 participants
  GRADE not reported

Biodentine vs Tempophore

Biodentine showed no clear difference in clinical failure compared with tempophore; GRADE not reported.

• Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes

  6 and 12 months
  RR 1.08 [0.07, 16.36]
  1 study · 56 participants
  GRADE not reported

Biodentine vs Mineral trioxide aggregate (MTA)

Biodentine showed no clear difference in clinical failure compared with mineral trioxide aggregate (MTA) (low certainty).

• Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes

  6 months
  RR 1.72 [0.42, 6.99]
  4 studies · 234 participants
  Low

Biodentine vs Propolis

Biodentine showed no clear difference in clinical failure compared with propolis; GRADE not reported.

• Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes

  6 months
  RR 0.33 [0.01, 7.81]
  1 study · 50 participants
  GRADE not reported