Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Benzodiazepines vs ANTIHISTAMINES + ANTIPSYCHOTICS

Global state: no improvement ‐ medium termAs defined in each study · psychosis‐induced aggression or agitation

Benzodiazepines may leads to higher global state: no improvement ‐ medium termAs defined in each study compared with antihistamines plus antipsychotics (low certainty).

1 finding from 1 review

Benzodiazepines vs placebo

Global state: no improvement ‐ medium termAs defined in each study · psychosis‐induced aggression or agitation

It is very uncertain whether benzodiazepines changes global state: no improvement ‐ medium termAs defined in each study compared with placebo (very low certainty).

1 finding from 1 review

BENZODIAZEPINES + ANTIPSYCHOTICS vs ANTIHISTAMINES + ANTIPSYCHOTICS

Global state: no improvement ‐ medium termAs defined in each study · psychosis‐induced aggression or agitation

It is very uncertain whether benzodiazepines plus antipsychotics changes global state: no improvement ‐ medium termAs defined in each study compared with antihistamines plus antipsychotics (very low certainty).

1 finding from 1 review

BENZODIAZEPINES + ANTIPSYCHOTICS vs same enzodiazepines

Global state: no improvement ‐ medium termAs defined in each study · psychosis‐induced aggression or agitation

Benzodiazepines + antipsychotics showed no clear difference in global state: no improvement ‐ lorazepam + risperidone vs lorazepam… compared with same enzodiazepines (low certainty).

1 finding from 1 review