Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews · Airways

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 1 · 14.3%Moderate 4 · 57.1%High 1 · 14.3%

Beclometasone/LABA vs LABA

Mortality (all‐cause) (dichotomous Peto method) · participants with stable stage 3 COPD, smokers and ex‐smokers with a minimum pack‐year history of 20

It is very uncertain whether beclometasone/LABA changes mortality (all‐cause) (dichotomous Peto method) compared with LABA (very low certainty).

1 finding from 1 review

Beclometasone/LABA vs LABA

Pneumonia · participants with stable stage 3 COPD, smokers and ex‐smokers with a minimum pack‐year history of 20

Beclometasone/LABA showed no clear difference in pneumonia: participants with at least one (dichotomous Peto odds… compared with LABA (low certainty).

1 finding from 1 review

Beclometasone/LABA vs LABA

Exacerbations · participants with stable stage 3 COPD, smokers and ex‐smokers with a minimum pack‐year history of 20

Beclometasone/LABA showed no clear difference in exacerbations: participants with at least one (dichotomous) compared with LABA (moderate certainty).

1 finding from 1 review

Beclometasone/LABA vs LABA

Withdrawal (all‐cause) · participants with stable stage 3 COPD, smokers and ex‐smokers with a minimum pack‐year history of 20

Beclometasone/LABA showed no clear difference in withdrawal (all‐cause) compared with LABA (moderate certainty).

1 finding from 1 review