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What do systematic reviews say?

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Evidence found and GRADE certainty

41 questions · 41 findings · 2 reviews · Drugs and Alcohol

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No studies found 17 · 41.5%GRADE not reported 0 · 0%Very low 17 · 41.5%Low 0 · 0%Moderate 3 · 7.3%High 4 · 9.8%

Baclofen vs placebo

AW seizures · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

AW seizures · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

AW delirium · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

Global improvement · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

Craving · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

AEs · people with alcohol withdrawal

It is very uncertain whether baclofen changes AEs compared with diazepam (very low certainty).

1 finding from 1 review

Baclofen vs diazepam

Severe AEs · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs diazepam

Leaving the study early · people with alcohol withdrawal

It is very uncertain whether baclofen changes dropouts compared with diazepam (very low certainty).

1 finding from 1 review

Baclofen vs diazepam

Dropouts due to adverse events · people with alcohol withdrawal

It is very uncertain whether baclofen changes dropouts due to AEs compared with diazepam (very low certainty).

1 finding from 1 review

Baclofen vs placebo

AW delirium · people with alcohol withdrawal

The review found no eligible studies for this question.

1 finding from 1 review

Baclofen vs chlordiazepoxide

AW symptoms (CIWA‐Ar score) · people with alcohol withdrawal

It is very uncertain whether baclofen changes AW symptoms (CIWA‐Ar score) compared with chlordiazepoxide (very low certainty).

1 finding from 1 review

Baclofen vs chlordiazepoxide

Global improvement · people with alcohol withdrawal

It is very uncertain whether baclofen changes global improvement compared with chlordiazepoxide (very low certainty).

1 finding from 1 review

Baclofen vs chlordiazepoxide

AEs · people with alcohol withdrawal

It is very uncertain whether baclofen changes AEs compared with chlordiazepoxide (very low certainty).

1 finding from 1 review

Baclofen vs chlordiazepoxide

Leaving the study early · people with alcohol withdrawal

It is very uncertain whether baclofen changes dropouts compared with chlordiazepoxide (very low certainty).

1 finding from 1 review

Baclofen vs chlordiazepoxide

Dropouts due to adverse events · people with alcohol withdrawal

It is very uncertain whether baclofen changes dropouts due to AEs compared with chlordiazepoxide (very low certainty).

1 finding from 1 review