Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Acute Respiratory Infections

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Azithromycin vs amoxicillin

Clinical cure (bacteriological per protocol analysis) · group A streptococcal pharyngitis

It is very uncertain whether azithromycin changes clinical cure (bacteriological per protocol analysis) compared with amoxicillin (very low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 0.29 [0.11, 0.73]
1 study · 482 participants
Very low

Azithromycin vs amoxicillin

Relapse · group A streptococcal pharyngitis

It is very uncertain whether azithromycin changes relapse (ITT analysis) compared with amoxicillin (very low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 0.75 [0.55, 1.02]
1 study · 673 participants
Very low

Azithromycin vs amoxicillin

Relapse (bacteriological per protocol analysis) · group A streptococcal pharyngitis

It is very uncertain whether azithromycin changes relapse (bacteriological per protocol analysis) compared with amoxicillin (very low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 0.88 [0.43, 1.82]
1 study · 422 participants
Very low

Azithromycin vs amoxicillin

Adverse events (ITT analysis) · group A streptococcal pharyngitis

It is very uncertain whether azithromycin changes adverse events (ITT analysis) compared with amoxicillin (very low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 2.67 [1.78, 3.99]
1 study · 673 participants
Very low

Azithromycin vs amoxicillin

Clinical cure · group A streptococcal pharyngitis

It is very uncertain whether azithromycin changes clinical cure (ITT analysis) compared with amoxicillin (very low certainty).

1 finding from 1 review

Different antibiotic treatments for group A streptococcal pharyngitis 2023 · Cochrane Headline outcomes only
OR 0.76 [0.55, 1.05]
1 study · 673 participants
Very low