QoL · children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
FEV1 % predicted: absolute change from baseline · children with cystic fibrosis
1 finding from 1 review
Time to next pulmonary exacerbation · children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events: number of treatment‐related adverse events · children with cystic fibrosis
1 finding from 1 review
Hospital admissions · children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
New acquisition of CF pathogens: PA (mean change in PA count (log10 PA CFU/g sputum)) · children with cystic fibrosis
1 finding from 1 review
Need for additional antibiotic therapy · children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
QoL · children with cystic fibrosis
1 finding from 1 review
FEV1 % predicted · children with cystic fibrosis
1 finding from 1 review
Pulmonary exacerbations · children with cystic fibrosis
1 finding from 1 review
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Azithromycin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
3 findings from 1 review
MD -0.57 [-1.08, -0.07]
6 studies · 216 participants
GRADE not reported
MD -0.77 [-2.33, 0.79]
2 studies · 110 participants
Very low
MD -0.60 [-1.02, -0.18]
7 studies · 258 participants
GRADE not reported
Percentage of closed pockets · Adults with periodontitis (chronic and aggressive)
Azithromycin + SRP showed no clear difference in percentage of closed pockets compared with SRP; GRADE not reported.
2 findings from 1 review
Percentage of bleeding on probing (BOP) · Adults with periodontitis (chronic and aggressive)
Azithromycin + SRP led to lower percentage of bleeding on probing (BOP) compared with SRP; GRADE not reported.
3 findings from 1 review
MD -3.32 [-6.23, -0.42]
6 studies · 228 participants
GRADE not reported
MD -1.28 [-4.32, 1.76]
2 studies · 110 participants
Very low
MD -3.18 [-7.01, 0.65]
6 studies · 216 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether azithromycin + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).
3 findings from 1 review
MD -0.59 [-1.27, 0.08]
2 studies · 110 participants
Very low
MD -0.43 [-0.77, -0.10]
7 studies · 258 participants
GRADE not reported
MD -0.51 [-0.83, -0.19]
6 studies · 216 participants
GRADE not reported
Antimicrobial resistance · Adults with periodontitis (chronic and aggressive)
The review found no eligible studies for this question.
1 finding from 1 review
Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether azithromycin + SRP changes adverse events compared with SRP (very low certainty).
1 finding from 1 review
1 study reported diarrhoea, headache or dizziness, metallic taste, and general unwellness by 4 participants from the intervention group and 3 from the control group. In 1 study none of the participants reported any…
2 studies · 110 participants
Very low
FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis
1 finding from 1 review
Time to next pulmonary exacerbation · adults and children with cystic fibrosis
1 finding from 1 review
Adverse events: number of mild treatment‐related adverse events · adults and children with cystic fibrosis
1 finding from 1 review