Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

60 questions · 60 findings · 5 reviews

No studies found 16 · 26.7%GRADE not reported 8 · 13.3%Very low 8 · 13.3%Low 8 · 13.3%Moderate 16 · 26.7%High 4 · 6.7%

Azithromycin vs doxycycline

Microbiological failure Men · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

Azithromycin probably leads to higher microbiological failure Men compared with doxycycline (moderate certainty).

1 finding from 1 review

Azithromycin vs doxycycline

Microbiological failure Women · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

It is very uncertain whether azithromycin changes microbiological failure Women compared with doxycycline (very low certainty).

1 finding from 1 review

Azithromycin vs doxycycline

Adverse events Men · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

Azithromycin showed no clear difference in adverse events Men compared with doxycycline (low certainty).

1 finding from 1 review

Azithromycin vs doxycycline

Adverse events Men and women · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

Azithromycin probably leads to lower adverse events Men and women compared with doxycycline (moderate certainty).

1 finding from 1 review

Azithromycin vs doxycycline

Clinical failure Men · men and non‐pregnant women with symptomatic (uterine cervicitis and urethritis), or asymptomatic genital CT infection, diagnosed by cell…

Azithromycin showed no clear difference in clinical failure Men compared with doxycycline (low certainty).

1 finding from 1 review

Oral azithromycin vs control

Ocular chlamydia trachomatis infection · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Oral azithromycin vs control

Antibiotic resistance · people (any age) with active trachoma

Oral azithromycin led to lower antibiotic resistance Proportion of samples showing evidence of… compared with control; GRADE not reported.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    4 studies · 1354 participants
    GRADE not reported

Oral azithromycin vs control

Active trachoma · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found