Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 1 · 25%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Azelaic acid vs clindamycin

Treatment withdrawal · participants with acne

Azelaic acid showed no clear difference in withdrawal for any reason (long term: treatment duration > 8 weeks) compared with clindamycin (low certainty).

1 finding from 1 review

Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
RR 1.3 [0.48, 3.56]
2 studies · 329 participants
Low

Azelaic acid vs clindamycin

Minor adverse events · participants with acne

Azelaic acid showed no clear difference in total number of participants who experienced at least one minor… compared with clindamycin (low certainty).

1 finding from 1 review

Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
RR 1.5 [0.67, 3.35]
1 study · 100 participants
Low

Azelaic acid vs clindamycin

Quality of life · participants with acne

The review found no eligible studies for this question.

1 finding from 1 review

Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Azelaic acid vs clindamycin

Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks) · participants with acne

Azelaic acid showed no clear difference in participants' global self‐assessment of acne improvement Good or… compared with clindamycin (low certainty).

1 finding from 1 review

Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
RR 1.13 [0.92, 1.38]
1 study · 229 participants
Low