Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · Skin

No studies found 2 · 25%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 12.5%High 5 · 62.5%

Azelaic acid vs placebo

Participant‐assessed improvement in rosacea severity · Participants with rosacea

Azelaic acid leads to higher participant‐assessed improvement in rosacea severity Marked… compared with placebo (high certainty).

1 finding from 1 review

Azelaic acid vs placebo

Proportion of participants with adverse event · Participants with rosacea
1 finding from 1 review

Azelaic acid vs placebo

Physician‐assessed improvement in rosacea severity · Participants with rosacea

Azelaic acid leads to higher physician‐assessed improvement in rosacea severity compared with placebo (high certainty).

1 finding from 1 review

Azelaic acid vs placebo

Time needed until improvement of the skin lesions · Participants with rosacea
1 finding from 1 review

Azelaic acid vs placebo

Duration of remission ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Azelaic acid vs placebo

HRQOL ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review