Azathioprine may leads to lower failure to maintain remission compared with placebo (low certainty).
It is very uncertain whether azathioprine changes any adverse events compared with placebo (very low certainty).
It is very uncertain whether azathioprine changes withdrawal due to adverse event compared with placebo (very low certainty).
It is very uncertain whether azathioprine changes failure to maintain remission compared with sulfasalazine (very low certainty).
Azathioprine showed no clear difference in adverse events compared with infliximab (moderate certainty).
Azathioprine showed no clear difference in withdrawals due to adverse events compared with infliximab (moderate certainty).
Azathioprine showed no clear difference in serious adverse events compared with infliximab (moderate certainty).
Azathioprine probably leads to lower clinical remission compared with infliximab (moderate certainty).
Azathioprine probably leads to lower clinical remission off steroids compared with infliximab (moderate certainty).
Azathioprine probably leads to lower mucosal healing compared with infliximab (moderate certainty).
It is very uncertain whether azathioprine changes withdrawals due to adverse events compared with budesonide (very low certainty).
It is very uncertain whether azathioprine changes serious adverse events compared with budesonide (very low certainty).
Azathioprine may leads to higher maintenance of remission compared with budesonide (low certainty).
It is very uncertain whether azathioprine (AZA) changes failure to maintain remission compared with cyclosporin of remission (very low certainty).
Azathioprine + infliximab probably leads to higher clinical remission compared with infliximab (moderate certainty).
Azathioprine + infliximab probably leads to higher clinical remission off steroids compared with infliximab (moderate certainty).
Azathioprine + infliximab probably leads to higher mucosal healing compared with infliximab (moderate certainty).
Azathioprine + infliximab showed no clear difference in adverse events compared with infliximab (moderate certainty).
Azathioprine + infliximab showed no clear difference in withdrawals due to adverse events compared with infliximab (moderate certainty).
Azathioprine + infliximab probably leads to lower serious adverse events compared with infliximab (moderate certainty).