What do systematic reviews say?

Azathioprine or 6‐mercaptopurine vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

It is very uncertain whether azathioprine or 6‐mercaptopurine changes radiologic relapse compared with 5‐aminosalicylic acid (very low certainty).

• Azathioprine and 6‐mercaptopurine for maintenance of surgically‐induced remission in Crohn's disease 2019 · Cochrane Headline outcomes only
  RR 0.92 [0.66, 1.28]
  1 study · 35 participants
  Very low

Azathioprine or 6‐mercaptopurine vs anti TNF‐ɑ

• Azathioprine and 6‐mercaptopurine for maintenance of surgically‐induced remission in Crohn's disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 117 participants
  GRADE not reported

Azathioprine or 6‐mercaptopurine vs placebo

The review found no eligible studies for this question.

• Azathioprine and 6‐mercaptopurine for maintenance of surgically‐induced remission in Crohn's disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found