Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 80%Low 1 · 20%Moderate 0 · 0%High 0 · 0%

Azathioprine vs sulfasalazine

Failure to maintain remission · Patients with quiescent ulcerative colitis

It is very uncertain whether azathioprine changes failure to maintain remission compared with sulfasalazine (very low certainty).

1 finding from 1 review

Azathioprine and 6‐mercaptopurine for maintenance of remission in ulcerative colitis 2016 · Cochrane Headline outcomes only
RR 1.52 [0.66, 3.5]
1 study · 25 participants
Very low

Azathioprine or 6‐mercaptopurine vs mesalazine or sulfasalazine

Maintenance of remission · maintenance of remission in Crohn's disease

Azathioprine or 6‐mercaptopurine showed no clear difference in maintenance of remission compared with mesalazine or sulfasalazine (low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 1.09 [0.88, 1.34]
2 studies · 166 participants
Low

Azathioprine or 6‐mercaptopurine vs mesalazine or sulfasalazine

Adverse events · maintenance of remission in Crohn's disease

It is very uncertain whether azathioprine or 6‐mercaptopurine changes adverse events compared with mesalazine or sulfasalazine (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 8.77 [0.54, 142.51]
1 study · 45 participants
Very low

Azathioprine or 6‐mercaptopurine vs mesalazine or sulfasalazine

Withdrawals due to adverse events · maintenance of remission in Crohn's disease

It is very uncertain whether azathioprine or 6‐mercaptopurine changes withdrawals due to adverse events compared with mesalazine or sulfasalazine (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 1.86 [0.87, 3.97]
2 studies · 290 participants
Very low

Azathioprine or 6‐mercaptopurine vs mesalazine or sulfasalazine

Serious adverse events · maintenance of remission in Crohn's disease

It is very uncertain whether azathioprine or 6‐mercaptopurine changes serious adverse events compared with mesalazine or sulfasalazine (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 9.37 [1.84, 47.72]
2 studies · 235 participants
Very low