Findings

What do systematic reviews say?

6 questions · 7 findings · 1 reviews · Kidney and Transplant

No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 85.7%High 0 · 0%

Death (all causes) · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in death (median compared with cyclophosphamide (moderate certainty).

1 finding from 1 review

Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
RR 0.77 [0.35, 1.72]
1 study · 144 participants
Moderate

Kidney function · adults with renal vasculitis for maintenance therapy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Dialysis · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in dialysis (median compared with cyclophosphamide (moderate certainty).

1 finding from 1 review

Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
RR 1.65 [0.57, 4.79]
1 study · 144 participants
Moderate

Relapse · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in relapse at 18 months compared with cyclophosphamide (moderate certainty).

2 findings from 1 review

Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
RR 1.13 [0.51, 2.5]
1 study · 144 participants
Moderate
Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
RR 1.46 [1, 2.14]
1 study · 144 participants
Moderate

Serious adverse events · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in serious adverse events compared with cyclophosphamide (moderate certainty).

1 finding from 1 review

Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
RR 1.18 [0.45, 3.07]
1 study · 144 participants
Moderate

Infections · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in infections compared with cyclophosphamide (moderate certainty).

1 finding from 1 review

Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
RR 1.03 [0.51, 2.06]
1 study · 144 participants
Moderate