Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

19 questions · 20 findings · 2 reviews · Kidney and Transplant

No studies found 3 · 15%GRADE not reported 0 · 0%Very low 2 · 10%Low 8 · 40%Moderate 7 · 35%High 0 · 0%

Azathioprine vs cyclophosphamide

Relapse · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in relapse at 18 months compared with cyclophosphamide (moderate certainty).

2 findings from 1 review

Azathioprine vs cyclophosphamide

Serious adverse events · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in serious adverse events compared with cyclophosphamide (moderate certainty).

1 finding from 1 review

Azathioprine vs methotrexate

Adverse event causing death or study drug discontinuation · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in adverse events causing death or study drug discontinuation compared with methotrexate (low certainty).

1 finding from 1 review